On March 11-12, 2025 the Starling Institute and Carnegie Endowment for International Peace’s Global Order & Institutions Program gathered about 30 participants, mostly U.S.-based, at the Pocantico Center of the Rockefeller Brothers Fund in Tarrytown, New York to discuss the global risks and opportunities of dramatic geopolitical shifts, not least in American foreign policy. Discussion focused on the implications of these developments for renewed multilateral cooperation.